# Pharmarcokinetics for Experimental Rheumatoid Arthritis treatment

Canonical: https://abierto.us/opportunities/36c24526q0669

- Solicitation number: 36C24526Q0669
- Notice type: Presolicitation (first published as sources sought)
- Status: Closed. Deadline was July 31, 2026 at 9:00 AM EDT
- Department: Department of Veterans Affairs
- Contracting office: 245-Network Contract Office 5 (36C245)
- NAICS: 112990 All Other Animal Production
- Product or service code: AJ13 General Science & Technology R&D Svcs; General Science & Technology; Experimental Development
- First posted: July 16, 2026
- Last posted: July 16, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/750f005515244b6eb709587fd0f1a412/view

## Description

PRE SOLICITATION NOTICE Department of Veterans Affairs Network Contracting Office (NCO)

**05 Title:** A Joint Targeted Drug Delivery Approach for Arthritis Therapy Toxicity and Pharmacokinetics The Department of Veterans Affairs (VA), Network Contracting Office (NCO) 05, intends to issue a solicitation for preclinical toxicology and pharmacokinetic (PK) studies to support advancement of an experimental joint targeted liposomal delivery system for Rheumatoid Arthritis therapy. This requirement involves GLP compliant toxicity studies and GLP or non GLP PK studies in adult rats.

The forthcoming solicitation will seek a contractor capable of performing: GLP single dose IV toxicity studies including clinical observations, weight/food intake monitoring, blood chemistry assessments, necropsy, and histopathology. GLP or non GLP pharmacokinetic studies including IV dosing, timed blood collection, plasma processing and storage, LC MS/MS analysis of dexamethasone and 6 hydroxydexamethasone, and calculation of PK parameters.

A comprehensive final written report covering toxicity results, PK data, and analytical findings. Place of performance will be the contractor s laboratory. The anticipated period of performance is one year, approximately September 15, 2026 through September 14, 2027. This notice is issued solely for informational purposes. A formal solicitation and the Government s acquisition strategy will be issued after completion of market research. This notice does not constitute a solicitation and does not commit the Government to award a contract.

**Point of Contact:**

**Robert O Keefe Jr., Contract Specialist Email:** robert.okeefejr@va.gov

## Publications

- July 16, 2026: Sources sought, due July 31, 2026 at 9:00 AM EDT. Notice 53aad037adb742b6997988dc8854eeea. https://sam.gov/workspace/contract/opp/53aad037adb742b6997988dc8854eeea/view
- July 16, 2026: Presolicitation, due July 31, 2026 at 9:00 AM EDT. Notice 750f005515244b6eb709587fd0f1a412. https://sam.gov/workspace/contract/opp/750f005515244b6eb709587fd0f1a412/view

## Points of contact

- Robert O'Keefe Jr., Contracting Officer, robert.okeefejr@va.gov

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/36c24526q0669.