# Flow Imaging Microscopy combined with Light Obscuration Capabilities

Canonical: https://abierto.us/opportunities/1333nd26qnb640309

- Solicitation number: 1333ND26QNB640309
- Notice type: Combined synopsis and solicitation
- Status: Closed. Deadline was September 4, 2026 at 9:00 AM EDT
- Department: Department of Commerce
- Agency: National Institute of Standards and Technology
- Contracting office: Department of Commerce NIST (1333ND)
- NAICS: 334510 Electromedical and Electrotherapeutic Apparatus Manufacturing
- Product or service code: 6630 Chemical Analysis Instruments
- Place of performance: Gaithersburg, Maryland
- First posted: August 4, 2026
- Last posted: August 28, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/ee9bc9b951144d8ca405471af6d6fca6/view

## Description

The purpose of Admendment 0001 is to update the SOW and Terms and conditions to include Option years for the service agreement.

The purpose of Amendment 0001 is as follows:

1. Extend due date for offers to September 4, 2026.;

2. Revised Title to read "flow imaging instrument combined with light obscuration capabilities" 3. Provide updated Statement of Work and Attachment 2 - Terms and Conditions to include Option Periods for Service Agreement

The Bioprocess Measurements Group at the National Institute of Standards and Technology (NIST) located at Gaithersburg, MD provides measurement science and standards for robust characterization of biologically or synthetically derived particles that are relevant in the biomanufacturing industry. These particle types can be hard to distinguish, and regulatory guidelines require detailed characterization of these particles in drug products.

Industry currently relies heavily on flow imaging microscopy and light obscuration (compendial method) for characterizing these particles in their products. We are requesting an updated flow imaging instrument with light obscuration capabilities to replace two outdated, unsupported systems (Flow imaging and Light Obscuration) which no longer reflect instruments used in industry which limits data comparability and collaboration.

## Publications

- August 4, 2026: Combined synopsis and solicitation, due August 14, 2026 at 11:00 AM EDT. Notice f27af2d8fbf84db4a5e9e9bc5c283bb5. https://sam.gov/workspace/contract/opp/f27af2d8fbf84db4a5e9e9bc5c283bb5/view
- August 28, 2026: Combined synopsis and solicitation, due September 4, 2026 at 9:00 AM EDT. Notice ee9bc9b951144d8ca405471af6d6fca6. https://sam.gov/workspace/contract/opp/ee9bc9b951144d8ca405471af6d6fca6/view

## Points of contact

- Rene D. Edwards, rene.edwards@nist.gov, 3019756107
- Robert Singman, robert.singman@nist.gov, 3019756388

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/1333nd26qnb640309.